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Monday, August 3, 2020 | History

5 edition of Stunning, hibernation, and calcium in myocardial ischemia and reperfusion found in the catalog.

Stunning, hibernation, and calcium in myocardial ischemia and reperfusion

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  • 40 Currently reading

Published by Kluwer Academic in Boston .
Written in

    Subjects:
  • Myocardial stunning,
  • Myocardial hibernation,
  • Calcium -- Pathophysiology,
  • Calcium -- metabolism,
  • Myocardial Infarction -- complications,
  • Myocardial Reperfusion Injury -- physiopathology

  • Edition Notes

    Includes bibliographical references and indexes.

    Statementedited by Lionel H. Opie ; introductory article by Eugene Braunwald.
    ContributionsOpie, Lionel H.
    Classifications
    LC ClassificationsRC682.9 .S78 1992
    The Physical Object
    Pagination288 p. :
    Number of Pages288
    ID Numbers
    Open LibraryOL1714952M
    ISBN 100792317939
    LC Control Number92017257

    Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion. Lionel H. Opie. 30 Sep Paperback. US$ Add to basket. 18% off. Hibernation, and Calcium in Myocardial Ischemia and Reperfusion. Lionel H Opie. 30 Sep Paperback. unavailable. Try AbeBooks. Farmacos Para El Corazon. Lionel H Opie. Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality. Reperfusion strategies are the current standard therapy for AMI. However, they may result in paradoxical cardiomyocyte dysfunction, known as ischemic reperfusion injury (IRI). Different forms of IRI are recognized, of which only the first two are reversible: reperfusion-induced arrhythmias, myocardial stunning Cited by:

    Neutrophils and inflammatory cytokines have been implicated in ischemia/reperfusion injury. These observations bridge two fundamental areas of biology, cytokines, and free radical reactions. Ischemic injury occurs when the blood supply to an area of tissue is cut off. The incidence of ischemic injury is vast: myocardial infarction, stroke, and. The clinical manifestations of myocardial ischemia-reperfusion injury include arrhythmia, myocardial stunning, and no-reflow. Although lethal reperfusion injury in clinical practice is more difficult to identify, it is the most serious consequence of ischemia/reperfusion injury and is also the main reason preventing the ischemic myocardium Author: Suli Zhang, Jin Wang, Yunhui Du, Jianyu Shang, Li Wang, Jie Wang, Ke Wang, Kehua Bai, Tingting Lv, X.

    Mouse myocardial ischemia-reperfusion models are an effective method for cardiovascular research to simulate clinical acute or chronic heart dise Significant effort has been applied to develop and refine surgical approaches that produce ischemic events and reperfusion damage in the hearts of several different animal by:   Background It is widely accepted that edema occurs early in the ischemic zone and persists in stable form for at least 1 week after myocardial ischemia/reperfusion. However, there are no longitudinal studies covering from very early (minutes) to late (1 week) reperfusion stages confirming this phenomenon. Objectives This study sought to perform a comprehensive longitudinal imaging and Cited by:


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Stunning, hibernation, and calcium in myocardial ischemia and reperfusion Download PDF EPUB FB2

Stunning is potentially an important complication of myocardial reperfusion. In contrast, hibernation is an important complication of myocardial ischemia. Stunning This book presents different viewpoints on these subjects, taken from a series of peer-reviewed articles which first appeared in Cardiovascular Drugs and Therapy, and now in this book.

In Format: Paperback. Stunning, hibernation, and calcium in myocardial ischemia and reperfusion. Boston: Kluwer Academic, © (OCoLC) Material Type: Internet resource: Document Type: Book, Internet Resource: All Authors / Contributors: Lionel H Opie. Stunning is potentially an important complication of myocardial reperfusion.

In contrast, hibernation is an important complication of myocardial ischemia. This book presents different viewpoints on these subjects, taken from a series of peer-reviewed articles which first appeared in Cardiovascular Drugs and Therapy, and now in this book.

Acute myocardial infarction: Myocardial stunning occurs after acute myocardial infarction as evidenced by patients treated with reperfusion therapy who have shown near normal and calcium in myocardial ischemia and reperfusion book by 2 weeks.

[22] [23] Myocardial hibernation has been demonstrated in infarcted areas of the myocardium and also in areas remote from the area of infarct but Author: Yash Vaidya, Shaelyn Cavanaugh, Amit Dhamoon. Stunning is potentially an important complication of myocardial reperfusion.

In contrast, hibernation is an important complication of myocardial ischemia. This book presents different viewpoints on these subjects, taken from a series of peer-reviewed articles which first appeared in Cardiovascular Drugs and Therapy, and now in this book.4/5(1).

Get this from a library. Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion. [Lionel H Opie] -- Stunning is potentially an important complication of myocardial reperfusion. In contrast, hibernation is an important complication of myocardial ischemia.

This. John W. Calvert PhD, in Cellular and Molecular Pathobiology of Cardiovascular Disease, Myocardial Stunning. Myocardial stunning is defined as ‘the mechanical dysfunction that persists after reperfusion despite the absence of irreversible damage’.

10 It was first described by Heyndrickx and colleagues in11 when the authors reported that coronary occlusions in the dog lasting. Stunning is found following coronary angioplasty, thrombolysis, coronary vasospasm, and cardiopulmonary bypass.

Myocardial hibernation is a term used to describe the condition in which regional cardiac function is depressed due to chronic ischemia. Restoration of normal coronary flow (e.g., by coronary bypass) will restore normal function in.

Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion pp | Cite as Myocardial Stunning and Hibernation: Mechanisms and Clinical Implication AuthorsCited by: Myocardial Stunning.

Myocardial stunning is defined as ‘the mechanical dysfunction that persists after reperfusion despite the absence of irreversible damage’ It was first described by Heyndrickx and colleagues in ,11 when the authors reported that coronary occlusions in the dog lasting for periods not long enough to induce cell death produced prolonged periods of contractile.

Acute myocardial infarction (MI) is a major cause of death and disability worldwide. In patients with MI, the treatment of choice for reducing acute myocardial ischemic injury and limiting MI size is timely and effective myocardial reperfusion using either thombolytic therapy or primary percutaneous coronary intervention (PPCI).Cited by: Stunning.

Welcome,you are looking at books for reading, the Stunning, you will able to read or download in Pdf or ePub books and notice some of author may have lock the live reading for some of ore it need a FREE signup process to obtain the book. If it available for your country it will shown as book reader and user fully subscribe will benefit by having full access to all books.

(ebook) Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion () from Dymocks online store. Stunning is potentially an important complication of.

Myocardial injury in the setting of an acute myocardial infarction is the result of ischemic and reperfusion injury. Reperfusion therapies, including primary percutaneous coronary intervention and fibrinolytic therapy, promptly restore blood flow to ischemic myocardium and limit infarct size.

Paradoxically, however, the return of blood flow can. Isolated male and female rat hearts were subjected to or min of global ischemia and min of reperfusion, with or without PostC (i.e., 5 cycles of s reperfusion/ischemia immediately.

1. Background: from Ca 2+ paradox to oxygen paradox. Myocardial reperfusion injury, defined as a kind of cell death occurring secondary to transient ischaemia that is preventable by interventions applied at the time of reperfusion, 1–6 is now recognized as an important element of the pathophysiology of myocardial ischaemia–reperfusion.

However, its cellular and molecular Cited by: Ischemia/Reperfusion Injury (IRI) occurring with ischemia and restoration of blood flow to post-ischemic tissue, is associated with arrhythmias, myocardial necrosis and apoptosis resulting in increased mortality and morbidity.

Calcium overload, pH recovery, and ROS overproduction are major players in determining IRI Mitochondria play a pivotal File Size: 1MB. Acidosis During Early Reperfusion Prevents Myocardial Stunning in Perfused Ferret Hearts free calcium during ischemia and reperfusion in ferret hearts (abstr) features of hibernation.

Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion by Lio Stunning, Hibernation, and: $ Hibernation, Calcium and Stunning, Lio in by and Ischemia Myocardial Reperfusion Reperfusion Myocardial Ischemia Hibernation, in by Calcium and Stunning, and Lio.

Evaluation of myocardial ischaemia and infarct size. After 4 hours of reperfusion, the LAD was reoccluded at the original site, the ascending aorta was clamped and 1 mlkg −1 of 2% Evan's blue was injected into the coronary circulation to outline the ischaemic myocardium.

The heart was then stopped by an injection of potassium chloride Cited by:. In cardiology, hibernating myocardium is a state when some segments of the myocardium exhibit abnormalities of contractile function.

These abnormalities can be visualised with echocardiography, cardiac magnetic resonance imaging (CMR), nuclear medicine (PET) or rdiography: A wall motion abnormality at rest which improves during a low Conduction / arrhythmia: Bradycardia, Sinus. Stunning is potentially an important complication of myocardial reperfusion.

In contrast, hibernation is an important complication of myocardial ischemia. This book presents different viewpoints on these subjects, taken from a series of peer-reviewed articles which first appeared in Cardiovascular Drugs and Therapy, and now in this book.In this paper, we concluded that transient acidosis reperfusion conferred cardioprotection against myocardial ischemia reperfusion injury in isolated rat hearts through activating PI3K-Akt-eNOS pathway.

1. Introduction. During myocardial ischemia, tissue pH significantly declines and returns to normal after reperfusion. Recently, studies Cited by: 7.